منابع مشابه
Kidney Exchange with Immunosuppressants∗
This paper investigates implications of introducing immunosuppressants (or suppressants) in kidney exchange problems. We begin with the standard kidney exchange model without suppressants and define two versions of the top-trading cycles (TTC) solutions satisfying Pareto efficiency. We then extend the model by introducing suppressants that make a patient compatible with any donor by relaxing im...
متن کاملRelation to Immunosuppressants?
A 35-y-old woman with pyrexia of unknown origin was referred to the Nuclear Medicine Department for an 18FFDG PET scan. She had undergone heart–lung transplantation for secondary pulmonary hypertension 4 mo previously. After transplantation she developed organizing pneumonia proven on transbronchial biopsies for which she required treatment with pulsed methyl prednisolone. Three months after su...
متن کاملEffects of Immunosuppressants and Cytostatics
Beginning in 1967, our laboratory has published a number of investigations of the nonsyngeneic stem ceil-inactivation phenomenon (1-3). I t has been shown that, after transplantation of a mixture of allogeneic lymphoid and hemopoietic cells into lethally irradiated hosts, stem elements of the mixture are inactivated by allogenic lymphocytes of the graft. In other words, after transplantation of...
متن کاملCancer risk of immunosuppressants in manufacturing.
During the chemical and pharmaceutical production of active pharmaceutical substances which are intended for immunosuppressive therapy, the employees may be exposed to these substances via inhalation. Immunosuppressants are linked to development of certain types of cancers e.g., lymphoma or skin cancer in transplant patients. The development of these cancers in patients is linked to the level o...
متن کاملTargets of new immunosuppressants in renal transplantation
Although current immunosuppression is highly effective in avoiding acute rejection, it is associated with nephrotoxicity, cardiovascular morbidity, infection, and cancer. Thus, new drugs dealing with new mechanisms, as well as minimizing comorbidities, are warranted in renal transplantation. Few novel drugs are currently under investigation in Phase I, II, or III clinical trials. Belatacept is ...
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ژورنال
عنوان ژورنال: Reactions Weekly
سال: 2021
ISSN: ['1179-2051', '0114-9954']
DOI: https://doi.org/10.1007/s40278-021-07492-x